Can I Run Qwen 3.5 122B-A10B on NVIDIA L40S?

Name: LLM Configurator — GPU VRAM Checker
Author: LLM Configurator

作者： Jakub Rusinowski · 最后更新： 2026年9月11日

Not at Q4_K_M — that needs 73.7 GB and the NVIDIA L40S has 48 GB. Drop to Q2_K and it fits in 43.8 GB, with up to 16K of context.

The numbers

Quantize to Q2_K. That is the cheapest fix — it costs some quality but no money.

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Running Qwen 3.5 122B-A10B on this card:

NVIDIA L40S 48GB

48 GB VRAM · 350 W board power

2026年价格波动较大——请以当前商品页价格为准。

Won't fit — rent Qwen 3.5 122B-A10B instead

Qwen 3.5 122B-A10B needs ~74 GB but this GPU has 48 GB. Rent a A100 (80 GB)-class GPU by the hour instead of buying one:

Affiliate links — we may earn a commission if you sign up, at no extra cost to you.

Vast.ai $0.77/hr · typical low · varies

RunPod $1.39/hr

Cloud rates verified 2026-07 — estimates, and marketplace prices vary. Buying price is GPU MSRP only, not a full PC.

Qwen 3.5 397B-A17B — does not fit (134.0 GB)
Qwen 3.5 35B-A3B — runs (21.1 GB)
Qwen 3.5 27B — runs (16.3 GB)
Qwen 3.5 9B — runs (5.4 GB)
Qwen 3.5 4B — runs (2.4 GB)
Qwen 3.5 2B — runs (1.2 GB)
Qwen 3.5 0.8B — runs (0.5 GB)