Can I Run GPT-OSS on AMD Ryzen AI Max+ 395?
Autor: Jakub Rusinowski · Ostatnia aktualizacja: 15 sierpnia 2026
Yes, comfortably — GPT-OSS 120B at Q4_K_M needs 71.6 GB at 8K context (70.5 GB weights + 1.1 GB KV cache/overhead), leaving ~56.4 GB of the AMD Ryzen AI Max+ 395's 128 GB, at ~43 tok/s (est.), with room for up to 128K context.
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AMD Ryzen AI Max+ 395 Specs
| VRAM | 128 GB |
| Memory Bandwidth | 256 GB/s |
GPT-OSS 120B on the AMD Ryzen AI Max+ 395: VRAM by quantization
| Quant | VRAM needed | Fits 128 GB? | Max context | Whole PC |
|---|---|---|---|---|
| F16 | 234.7 GB | ✗ No | — | — |
| Q8_0 | 125.2 GB | ✓ Yes | 64K | — |
| Q6_K | 96.9 GB | ✓ Yes | 128K | — |
| Q5_K_M | 83.9 GB | ✓ Yes | 128K | — |
| Q4_K_M | 71.6 GB | ✓ Yes | 128K | — |
| Q3_K_M | 50.9 GB | ✓ Yes | 128K | — |
| Q2_K | 39.5 GB | ✓ Yes | 128K | — |
Assumes an 8K-token context with an f16 KV cache. A longer window needs more; a quantized KV cache needs less. “Max context” is the largest window that still fits in 128 GB. Figures are estimates from parameter count, quantization and memory bandwidth — the analyzer lets you tune KV-cache quant and context.
Context costs VRAM too. At Q4_K_M on the AMD Ryzen AI Max+ 395: 8K 71.6 GB · 32K 72.6 GB · 128K 76.2 GB. Every window this model publishes still fits 128 GB.
No compatible GPU? GPT-OSS 120B on 96 GB of system RAM, CPU only: runs, but it is tight.
GPT-OSS Sizes That Fit the AMD Ryzen AI Max+ 395 (at 8K context)
| GPT-OSS 120B | Q4_K_M · 71.6 GB at 8K context · ~43 tok/s (est.) |
| GPT-OSS 20B | MXFP4 · 12.1 GB at 8K context · ~64 tok/s (est.) |
GPT-OSS needs ~72 GB but this GPU has 128 GB. Rent a A100 (80 GB)-class GPU by the hour instead of buying one:
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Cloud rates verified 2026-07 — estimates, and marketplace prices vary. Buying price is GPU MSRP only, not a full PC.
FAQ
Is the AMD Ryzen AI Max+ 395 enough to run GPT-OSS locally?
Yes, comfortably — GPT-OSS 120B at Q4_K_M needs 71.6 GB at 8K context (70.5 GB weights + 1.1 GB KV cache/overhead), leaving ~56.4 GB of the AMD Ryzen AI Max+ 395's 128 GB, at ~43 tok/s (est.), with room for up to 128K context.
What's the best GPT-OSS size for the AMD Ryzen AI Max+ 395?
GPT-OSS 120B at Q4_K_M quantization needs 71.6 GB at 8K context (70.5 GB weights + 1.1 GB KV cache/overhead), estimated ~43 tokens/sec, up to 128K context.
Every GPT-OSS size on the AMD Ryzen AI Max+ 395
| Size | VRAM at 8K | Verdict | Speed |
|---|---|---|---|
| GPT-OSS 120B | 71.6 GB | Runs | ~43 tok/s |
| GPT-OSS 20B | 12.1 GB | Runs | ~64 tok/s |
GPT-OSS on Other GPUs
Popular Models on the AMD Ryzen AI Max+ 395
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Troubleshooting
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← Can I Run It? | GPT-OSS Model Page | AMD Ryzen AI Max+ 395 GPU Page | VRAM calculator | Check Your Hardware