Can I Run Qwen 2.5 14B Instruct on NVIDIA RTX 6000 Ada Generation?

Written by Jakub Rusinowski · Last updated September 11, 2026

Yes. Qwen 2.5 14B Instruct needs 8.5 GB at Q4_K_M and the NVIDIA RTX 6000 Ada Generation has 48 GB, leaving about 39.5 GB of headroom, at roughly 79 tok/s (estimated) with room for up to 128K of context.

The numbers

ModelQwen 2.5 14B Instruct
Parameters14B
QuantizationQ4_K_M
VRAM needed8.5 GB
NVIDIA RTX 6000 Ada Generation VRAM48 GB
VerdictRuns
Max context128K
Estimated speed~79 tok/s

What to do next

Nothing to change — run it at Q4_K_M. If you want more capability, check whether the next size up also fits.

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Running Qwen 2.5 14B Instruct on this card:

NVIDIA RTX 6000 Ada Generation 48GB
48 GB VRAM · 300 W board power
2026 prices are volatile — check the current listing.
Check price on Amazon

Buy vs. rent Qwen 2.5 14B Instruct
Buy the GPU
~$6,799
NVIDIA RTX 6000 Ada Generation · MSRP
Rent by the hour
from $0.34/hr
RTX 4090 (24 GB) class

At 2 hrs/day, buying (~$6,799) beats renting at $0.34/hr after about 27.8 years.

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RunPod $0.34/hr
Rent on RunPod →
Vast.ai $0.35/hr · typical low · varies
Rent on Vast.ai →

Cloud rates verified 2026-07 — estimates, and marketplace prices vary. Buying price is GPU MSRP only, not a full PC.

Other Qwen 2.5 Family sizes on the NVIDIA RTX 6000 Ada Generation

Qwen 2.5 14B Instruct on nearby hardware

All Qwen 2.5 Family sizes on the NVIDIA RTX 6000 Ada Generation | VRAM calculator for Qwen 2.5 14B Instruct | NVIDIA RTX 6000 Ada Generation GPU page | Check your hardware